Sarcomas is a malignant solid tumor with high heterogeneity, which includes a large number of unique subtypes, more than 60 types. In recent years, targeted therapy based on the molecular and genetic phenotype of individual sarcomas has been a promising option for the treatment of sarcomas, meanwhile, several drugs have been approved for use to treat sarcomas.

Although some of the oncogenic factors and pathways that drive the development of sarcoma genesis have been identified, and targeted therapies have been developed, the treatment effectiveness of sarcomas still faces a great challenge.