Deciphering the Cascade: The Vital Role of C3b Deposition in Therapy
Deciphering the Cascade: The Vital Role of C3b Deposition in Therapy
The complement system acts as a double-edged sword. While it is a guardian of innate immunity, its uncontrolled activation—marked by the rapid opsonization of surfaces with C3b fragments—is a primary driver of tissue damage in rare diseases and chronic inflammation.   For drug developers, the ability to precisely quantify C3b deposition is no longer just a laboratory...
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