Allopurinol: A Cornerstone Xanthine Oxidase Inhibitor for...

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2026-05-29 07:17:03 -

Allopurinol: A Cornerstone Xanthine Oxidase Inhibitor for Hyperuricemia and Gout Management

What is Allopurinol? Allopurinol is a classic small-molecule purine analogue that has long been widely used for the intervention of hyperuricemia and gout-related diseases. Its core mechanism of action lies in the selective inhibition of xanthine oxidase (XO), thereby blocking the uric acid formation step in the purine metabolism pathway. Unlike drugs that simply promote uric acid excretion,...

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