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Eplerenone: A Highly Selective Mineralocorticoid Receptor Antagonist for Cardiovascular ProtectionWhat Is Eplerenone? Eplerenone is a highly selective aldosterone receptor antagonist (MRA) with a well-defined and stable clinical position in the treatment of cardiovascular diseases. From a chemical biology perspective, eplerenone selectively binds to mineralocorticoid receptors (MRs) with high affinity, blocking aldosterone-mediated gene transcriptional regulation, thereby inhibiting sodium...0 Comentários 0 Compartilhamentos 1KB Visualizações 0 Anterior